A3P Purification DSP

Clarification / Chromatography / Nanofiltration / Concentration / Diafiltration

Location

Lyon - Mercure Château Perrache

Date

November 29th

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Format

Conferences, Partner Sessions, Exhibition

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For more than 30 years, A3P has established its reputation by bringing together the various players in the biopharmaceutical industry to address the issues they face in their daily lives. A3P’s specificity lies in its unique ability to build networks of experts and opinion leaders working together to solve current and future issues and challenges in a pragmatic and efficient way.

Listening to the demands of our members, A3P has perceived that the implementation of purification schemes (or DSP) for biological active substances (Purified Bulk) was a source of questions and constraints both during the process development and routine commercial production phases.

The purification of biological substances from organ extracts, plants and human plasma has been widely known for almost a century. Similarly, the purification of recombinant proteins or vaccines expressed in genetically modified prokaryotic or eukaryotic cells has been widely industrialised for 50 years. Lastly, extraordinary medical prospects have been generated by gene and cell therapy and, in a completely different field, by Messenger RNA, which came to light again during the Covid crisis. The evocation of these different modalities makes us aware of the diversity of the purification processes used and their specificities.

Clarification, Chromatography, Nanofiltration, Concentration/Diafiltration, … all these operations must be selected, chained, optimized, industrialized in order to solve the challenge of the pharmaceutical industry, namely “to constantly increase the yield, purity and quality while accelerating clinical development and controlling production costs” in order to make these new therapies accessible to the greatest number.

In this context, A3P will organise a thematic day in Lyon on 29 November 2022, focusing on the “Challenges of implementing a purification strategy“. The day will include the presentation of case studies, workshops led by the 4 main suppliers in this sector and an exhibitors’ area to exchange and compare opinions.

Official language of the conferences: French
🎧 Simultaneous translation service: French / English

Tuesday, November 29th

Welcoming the participants
08:30
Vector Purification
Xavier ROBIN - Sanofi
09:00
Vector Purification
Stéphanie COLLOUD - ABL Europe
09:30
Break - Collation on the exhibition
10:00
Protein purification - Thymoglubulin
Maeva GUERCHET - Sanofi
11:00
Accelerate the development and clinical production of antibodies by setting up a purification platform
Marie CECILLE - Merck Biodevelopment / Thierry ZIEGLER - Igyxos
11:30
Industrial feedback on Purification of plasma proteins
Volker WEIMAR - Octapharma
12:00
Lunch break on the exhibition
12:30
Workshop sessions - See the proposed workshops
MERCK - REPLIGEN - SARTORIUS - THERMOFISHER
The interactive workshops organised with the partner companies are an opportunity for participants to familiarise themselves with their technical approach.
14:00
Workshop sessions - See the proposed workshops
MERCK - REPLIGEN - SARTORIUS - THERMOFISHER
The interactive workshops organised with the partner companies are an opportunity for participants to familiarise themselves with their technical approach.
15:00
Coffee break on the exhibition
16:00
The main stages of purification - Application to plasma proteins
Stéphanie JABY - LFB / Estelle DARNON - Technip
16:30
Development of a cGMP platform for the production and purification of pDNA for gene therapy and vaccines
Meriem BENDOUMA - PALL Corporation / Jean-Luc SCHLICK - RD Biotech
17:00
End of the event
17:30

Session 1 – 14:00

Cogent® Lab Systems - A family of modular and flexible systems for TFF at process development scale.
Laurine SELTZ & Benoît HUSSON - MERCK
Presentation of our new TFF CogentLab family for process developement scale. Main functionnalities and benefits will be highlighted during an interactive demo with participants.
Session 1
MERCK
Repligen, fully automated solutions for all your Tangential Filtration applications in hollow fibres or cassettes. Including real-time control, recording and monitoring of all parameters, as well as the concentration of your biomolecules.
Gilles VALARCHER & Eddy DE BOOK & Edouard ZORN - REPLIGEN
Our Repligen KR2i system is your ideal partner to realize and automate all your TFF applications in R&D, with GMP CFR21-Part11 option. In hollow fibres or in cassettes, in micro-filtration or ultra-filtration, for your proteins (mAbs, rProt, ADC, ...), your viral vectors (Lentiv, AAV, Plasmids, ...), your vaccines (mRNA, VLP, LNP, ...) and other exosomes or polymers. Coupling with the PAT UV-Vis FlowVPX system will allow you to add real-time monitoring and control of your product concentration.
Session 1
REPLIGEN
La platformisation des process de nouvelles modalités (vecteurs viraux, mRNA...): rêve ou réalité?
Fabien Rousset, Geoffrey Pressac, Marc Noverraz & Amélie Boulais - SARTORIUS
...
Session 1
SARTORIUS
Title to come
THERMOFISCHER
...
Session 1
THERMOFISCHER

Session 2 – 15:00

Cogent® Lab Systems - A family of modular and flexible systems for TFF at process development scale.
Laurine SELTZ & Benoît HUSSON - MERCK
PPresentation of our new TFF CogentLab family for process developement scale. Main functionnalities and benefits will be highlighted during an interactive demo with participants.
Session 2
MERCK
Repligen, fully automated solutions for all your Tangential Filtration applications in hollow fibres or cassettes. Including real-time control, recording and monitoring of all parameters, as well as the concentration of your biomolecules.
Gilles VALARCHER, Eddy DE BOOK & Edouard ZORN - REPLIGEN
Our Repligen KR2i system is your ideal partner to realize and automate all your TFF applications in R&D, with GMP CFR21-Part11 option. In hollow fibres or in cassettes, in micro-filtration or ultra-filtration, for your proteins (mAbs, rProt, ADC, ...), your viral vectors (Lentiv, AAV, Plasmids, ...), your vaccines (mRNA, VLP, LNP, ...) and other exosomes or polymers. Coupling with the PAT UV-Vis FlowVPX system will allow you to add real-time monitoring and control of your product concentration.
Session 2
REPLIGEN
Le futur de la purification des protéines thérapeutiques recombinantes
Fabien Rousset, Geoffrey Pressac, Marc Noverraz & Amélie Boulais - SARTORIUS
Résumé à venir
Session 2
SARTORIUS
Title to come
THERMOFISCHER
...
Session 2
THERMOFISCHER

Registration Form

A3P Purification DSP

After filling in this form, you will receive a copy by email

Registration fee : 600€ + A3P membership required (additional costs to be expected if you are not yet a member).
To know if you are a member, please contact us.
To know the fees, please refer to the Membership section of the website.

Exhibition plan

CompanyTT n°CompanyTT n°
19
2REPLIGEN10
3VERDOT Ips211
4SYSTEM C BIOPROCESS12
513
MERCK6SARTORIUS14
7ELSCOLAB15
THERMO FISHER SCIENTIFIC8PALL CORPORATION16

Services included with the Table Top

  • A dedicated exhibition space (2m deep x 3m wide) on which you can install your products and communication tools: umbrella stand, roll-up, display, product, … A basic equipment including a table 180 x 80 cm, 2 chairs and 1 electrical connection (2kw) without protection circuit breaker, the loan of a Nespresso coffee machine with pods
  • Breaks and meals as indicated in the programme
  • Unlimited Wifi
  • A badge that gives you free access to the entire technical and scientific programme
  • scientific programme
    The list of participants to the event

Exhibitor Form

A3P Purification DSP

Once this form completed, you will receive a copy by email

Tarif : 1600 € + mandatory membership (additional costs if you are not yet a member).
To find out if you are a member, please contact us.
To find out the rates, please refer to the Membership section of the website.

Contact

Depending on your requirements and preferences, you can contact Florian CANUTO or Hugo ROSE :

Phone : +33 (0)4 37 28 30 51
Email : fcanuto@a3pservices.com / hrose@a3pservices.com

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