La Vague 53
Low Endotoxin Recovery (LER) is today one of authorities serious concerns regarding pyrogen testing
Lipopolysaccharides / endotoxins are a subtype of pyrogens originating from the cell wall of gram-negative bacteria that are both extremely thermostable and very potent when brought into contact with the human immune system. But they are by no means the only possible pyrogenic contamination – and the growing complexity of biotechnological products increased the risk of having pyrogens present that originate from a variety of microorganisms and other sources.